Job DescriptionPostdoctoral opening in cardiac arrhythmia mechanisms is immediately available in the Poelzing lab. We are looking for highly motivated candidates with expertise in electrophysiology and whole-heart Langendorff perfusion. The project involves testing a novel hypothesis that structural integrity alone is sufficient to protect against arrhythmogenic conduction slowing in diseases associated with monogenic mutations in proteins expressed in the intercalated disc: gap junctions, sodium channels, desmosomes, and adherens junctions. Work will include optically mapping genetically engineered monogenic mutant mouse hearts, transmission and super-resolution microscopy. Novel peptide interventions targeting parts of the intercalated disc different from the areas of mutation will be perfused to test whether they can conceal or unmask an arrhythmogenic conduction phenotype.The environment of the Poelzing group is highly interdisciplinary and provides ample opportunities for scientific growth. The group has significant experience transitioning lab members to academic and industrial positions. Interested candidates should send their resume, statement of research goals, and at least three names for recommendation letters to Dr. Steven Poelzing (******).Required Qualifications• PhD in single cell and tissue/organ cardiac electrophysiology, molecular biology, genetics, and other relevant areas of biomedical sciences. PhD must be awarded no more than four years prior to the effective date of appointment with a minimum of one year eligibility remaining.• Be highly self-motivated and possess strong training in electrophysiology, molecular biology, animal studies, biochemical and histological assays.• Demonstrated publication of research findings in peer-reviewed journals.• Ability to receive training and write a post-doctoral fellowship application, participate in conferences for the intellectual exchange of research ideas, engage in existing and new collaborations within and outside Virginia Tech, and assist with training of undergraduate and graduate students, as needed.Preferred Qualifications• Candidates with experience in Matlab, cardiac electrophysiology and optical mapping experience of cell cultures or whole-heart.Appointment TypeRestrictedSalary InformationCommensurate with experienceReview DateAdditional InformationThe successful candidate will be required to have a criminal conviction check.About Virginia TechDedicated to its motto,Ut Prosim(That I May Serve), Virginia Tech pushes the boundaries of knowledge by taking a hands-on, transdisciplinary approach to preparing scholars to be leaders and problem-solvers. A comprehensive land-grant institution that enhances the quality of life in Virginia and throughout the world, Virginia Tech is an inclusive communitydedicated to knowledge, discovery, and creativity. The university offers more than 280 majors to a diverse enrollment of more than 36,000 undergraduate, graduate, and professional students in eight undergraduate colleges, a school of medicine, a veterinary medicinecollege, Graduate School , andHonors College . The university has a significant presence across Virginia, including theInnovation Campus in Northern Virginia; the Health Sciences and Technology Campus in Roanoke; sites in Newport News and Richmond; and numerousExtension offices andresearch centers . A leading global research institution, Virginia Tech conducts more than $500 million in research annually.Virginia Tech does not discriminate against employees, students, or applicants on the basis of age, color, disability, sex (including pregnancy), gender, gender identity, gender expression, genetic information, national origin, political affiliation, race, religion, sexual orientation, or military status, or otherwise discriminate against employees or applicants who inquire about, discuss, or disclose their compensation or the compensation of other employees or applicants, or on any other basis protected by law.If you are an individual with a disability and desire an accommodation, please contactBrittany Sheltonat ****** during regular business hours at least 10 business days prior to the event.
